FACTS ABOUT HYDROXYCHOLORQUINE



Hydroxychloroquine (sold under the name Plaquenil), and therefore the closely related chloroquine was approved within the 1950s mainly as anti-malaria treatments. Since then, the drugs are used for a good spectrum of diseases, including systemic LE (commonly referred to as “lupus”), atrophic arthritis, Sjogren’s syndrome, and even for complications of Lyme disease.

How Does It Work?

One aspect that has been relatively well understood is that these drugs work on the molecular level to disrupt critical cell processes, inactivating the body’s immune reaction. Since the natural immune reaction is liable for inflammation and other general disease symptoms (e.g. pain, fever, aching, etc.), this anti-immune process works to curtail systemic diseases like atrophic arthritis. As for malaria treatment, though Plaquenil is often indicated for the treatment of uncomplicated malaria, the precise mechanism by which this drug works to resolve malaria is essentially unknown.

What Are The Side Effects?
Though hydroxychloroquine could also be effective, it does have the potential of causing numerous side effects, including but not limited to headache, loss of appetite, nausea, vomiting, skin rash, etc.

Significant benefit:

A significant benefit of using these drugs is that they have been on the market and used for a long time, so a reasonable amount of information regarding actual patient reactions, side effects, and efficacy is available. Their use, especially for rheumatoid disorders and malaria has been relatively well supported by the planet Health Organization (WHO) and Centres for Disease Control and Prevention (CDC).

Indeed, there's still a big amount of labour left to be done before declaring these drugs as a viable treatment option for coronavirus, especially with regards to efficacy, safety, and long-term patient outcomes. However, if the scientific community can collaborate quickly enough to test these drugs, and if the results are true as promising as they initially seem, this could be a game-changer in curtailing the coronavirus pandemic.

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